Ketamine for PTSD: Emerging Evidence and Treatment Approaches
An evidence-based review of how ketamine therapy is being used to treat PTSD, including clinical trial data, proposed me…
Evidence-based information on ketamine treatment for depression, PTSD, chronic pain, and more.
Ketamine therapy has shown remarkable efficacy across a range of conditions.
When traditional antidepressants fail, ketamine offers rapid, evidence-based relief for severe depression.
Learn More →Ketamine offers rapid relief from PTSD symptoms, helping patients process trauma and reduce hyperarousal.
Learn More →Ketamine provides rapid anxiolytic effects for patients with severe, treatment-resistant anxiety.
Learn More →Ketamine targets the central sensitization underlying chronic pain, offering relief when other options fail.
Learn More →Emerging research shows ketamine can rapidly reduce obsessive thoughts and compulsive behaviors.
Learn More →Ketamine is one of the only treatments shown to rapidly reduce suicidal thoughts within hours.
Learn More →Three simple steps to finding the right ketamine clinic for you
Browse our evidence-based Knowledge Hub to understand conditions, treatment types, and what to expect.
Browse ArticlesSearch our vetted directory of 350+ ketamine providers by state to find clinics in your area.
Search DirectoryContact a clinic directly to request a free consultation — no commitment, no cost.
Get StartedReal experiences from patients who found relief through ketamine therapy
After years of trying different medications for my depression, ketamine therapy was the breakthrough I needed. Within the first session, I felt a shift I hadn't experienced in over a decade.
The chronic pain from my CRPS was unbearable. Ketamine infusions gave me my life back. I can finally play with my kids again.
I was skeptical at first, but the results speak for themselves. My anxiety is manageable for the first time in years, and the team at my clinic made me feel safe throughout the entire process.
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Find evidence-based ketamine therapy providers in your local area.
Common questions about ketamine therapy answered by our editorial team
Ketamine therapy involves the medical use of ketamine — originally developed as an anesthetic — to treat conditions like depression, PTSD, anxiety, chronic pain, and OCD. It is administered under medical supervision via IV infusion, intramuscular injection, or nasal spray (Spravato).
Spravato (esketamine nasal spray) is FDA-approved for treatment-resistant depression and major depressive disorder with suicidal ideation. IV and IM ketamine are used off-label for various mental health and pain conditions, which is a common and accepted medical practice.
Many patients report improvement within hours to days after their first session, unlike traditional antidepressants which can take weeks. A typical initial course involves 6 infusions over 2–3 weeks, with maintenance sessions as needed.
Common short-term side effects include dizziness, nausea, increased blood pressure, and dissociative sensations during the infusion. These typically resolve within 1–2 hours. Serious side effects are rare when administered in a clinical setting by trained providers.
IV ketamine infusions typically range from $400–$800 per session. Spravato may be partially covered by insurance. Many clinics offer package pricing for the initial 6-session series. Check with individual providers in our directory for specific pricing.
Use our provider directory to search by state and city. We list only vetted, licensed clinics. Look for providers who offer comprehensive consultations, have board-certified staff, and provide integration support alongside treatments.